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Some studies have found 10 to 15% less muscle loss in treated subjects compared to controls losing similar amounts of total weight
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K.GhoshdastidarB.GoyalG.BatinM.et al (2020)
Parkinsons disease study (Hauser et al., 1996): 600 mg IV twice daily for 30 days led to a 42% reduction in disability , with benefits lasting months after treatment cessation
Hot flashes are not painful, and you rarely observe any discomfort
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